Regenerative Medicine

In 2021, we initiated extensive research on dual-targeted organ repair under the National Major Research Transformation Program.

Previously, our focus was on systemic organ repair, which wasn’t able to target specific tissues. For instance, when oral stem cell factors are taken sublingually, they enter the bloodstream and are distributed throughout the body. While these factors can help repair various organs—such as reducing liver damage and improving fibrosis or alleviating lung inflammation and promoting lung repair—their impact is often diminished. This is because the stem cell factors are dispersed systemically, lowering the concentration in the specific organ in need of repair, thus reducing their effectiveness.

To address this, in 2021, we developed a method to guide stem cell factors to specific organs using small-molecule compounds. By locally modifying these cytokines, we essentially created a “GPS” for targeted organ migration. This innovation allows us to focus the therapeutic effects of stem cell factors on specific organs, achieving more precise and effective repair.

For example, in liver-targeted therapies, we pre-treat Mesenchymal stem cells with Icariin, enabling them to secrete more liver-specific repair factors such as HGF and VEGF. The resulting product is encased in liposomes and modified with glycyrrhetinic acid. Once absorbed into the bloodstream, the glycyrrhetinic acid acts as a GPS, directing the cytokines to the liver, where they bind to the liver’s glycyrrhetinic acid receptors, releasing the therapeutic factors slowly and effectively. This approach allows for more precise and efficient tissue repair.

Through years of technological development, we have refined the process using stem cell subpopulation separation technology and serum-free culture methods. By leveraging the paracrine effects of living stem cells, we’ve created a product enriched with over 100 bioactive factors such as VEGF, FGF, G-CSF, EGF, PDGF, and SDF-1, as well as peptides like albumin, pancreatic, ginseng, and soy peptides. Using freeze-drying technology, we preserve the potency of these bioactive factors, ensuring they regulate stem cell survival, migration, homing, proliferation, and tissue repair.

Organ and Tissue Repair

• Pancreas: Promotes regeneration and improves insulin resistance.
• Liver: Repairs liver function, alleviates fibrosis, and enhances immunity.
• Vascular system: Promotes vascular regeneration, improves microcirculation, and reduces systemic inflammation.
• Heart: Improves cardiac function and alleviates myocardial ischemia.
• Intestines: Repairs intestinal barriers and regenerates colonic epithelial cells.
• Immune System: Activates hematopoiesis and improves the prognosis of radiotherapy and chemotherapy.

Suitable for Patients with:

Diabetes, hypertension, liver fibrosis, fatty liver, liver cirrhosis, coronary heart disease, cerebral infarction, stroke, Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), cerebellar atrophy, spinal cord injury, chronic pneumonia, pulmonary fibrosis, bronchitis, and intestinal mucosal lesions.

Dual Stem Cell Factor Therapy

We use a combination of animal umbilical cord stem cell factors, bovine spleen peptides, bird’s nest peptides, giant salamander peptides, ginseng stem cell factors, deer blood peptides, GABA, and more. This coordinated approach enables full-body repair and regeneration.

Advanced Freeze-Drying Technology

Our products use advanced freeze-drying methods with protective agents to maintain bioactive factor stability for 3 to 4 years at room temperature, preserving their efficacy. This prevents degradation from high temperatures and ensures long-lasting effectiveness.

Efficient Absorption

Unlike intravenous injections, our oral and sublingual products are absorbed directly through the oral mucosa, entering the bloodstream within 2-3 minutes. This avoids degradation in the digestive system and liver’s first-pass effect.

Safety and Quality Assurance

Each batch of our products undergoes rigorous testing for microbial contamination, heavy metals, and other physical and chemical indicators, ensuring the highest safety and quality standards.